Understanding Non-Insulin Injectable Therapies for Diabetes


Sharon Bergquist, MD    

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In recent years, the Food and Drug Administration (FDA) has approved two classes of diabetes medication that are injectable, but not insulin:

  • Glucagon-like peptide 1 (GLP-1) receptor agonists
  • Amylin analogs

GLP-1 Receptor Agonists

After we eat, our small intestine releases GLP-1, a type of naturally-occurring hormone called an incretin that tells our bodies we’re full. GLP-1 works by slowing the rate at which our stomach empties after eating and by helping the pancreas secrete more insulin; insulin then works with other appetite-regulating hormones to make us feel full. This process lowers blood sugar, suppresses appetite, and causes weight loss.

Advances in diabetes treatment have recently brought us non-insulin injectable medications, which can be a great option to help you control your diabetes and stay healthy.

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