Biologics Revolutionize Psoriatic Arthritis Treatment


Gina Garippo

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How Biologics Are Given

In the past 10 years, the treatment of psoriatic arthritis has dramatically improved thanks to the creation of biologic response modifier (or biologic) drugs. Biologics, which are made from living things such as human and animal proteins, target specific areas of the immune system that cause psoriatic arthritis.

The drugs have offered tremendous hope for those with moderate to severe psoriatic arthritis, providing treatment success, usually without serious side effects.

Biologic Drugs at Work

Unlike other systemic treatments for psoriatic arthritis that affect the entire immune system, biologic drugs are designed to weaken or block only certain parts of the immune system, such as tumor necrosis factor-alpha (TNF-alpha) and specific Interleukin (IL) molecules. TNF-alpha, a substance created in excess by people with psoriatic arthritis, triggers inflammation, which leads to joint damage, pain, stiffness, and swelling. Interleukins are a protein family of inflammatory mediators.

Today, we’ve seen many advances in treating the damage and pain of psoriatic arthritis. Watch as experts share the advice they give patients for managing the condition.

Medical Reviewer: William C. Lloyd III, MD, FACS Last Review Date: Apr 29, 2017

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