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10 Medications That Cause Dry Mouth

Over 400 medications can create dry mouth.

There are over 400 medications that can create the dry, parched feeling in your mouth referred to as "dry mouth." Most of these medications have an antiadrenergic / anticholinergic effect, meaning they block certain functions of your body's systems that help promote watery secretions from glands, like saliva. Studies say dry mouth can create problems with swallowing, chewing and dental decay. Familiarize yourself with a few commonly used types of medications that can lead to oral dryness.

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Medically Reviewed By: William C. Lloyd III, MD, FACS | Last Review Date:

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Medical References

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  2. Hattori T, Wang PL. Calcium antagonists cause dry mouth by inhibiting resting saliva secretion. Life Sci. 2007 Aug 2;81(8):683-90. Epub 2007 Jul 18.
  3. Scully, C. Drug effects on salivary glands: dry mouth. Oral Diseases. 2003 July;9(4):165-76. http://onlinelibrary.wiley.com/doi/10.1034/j.1601-0825.2003.03967.x/full
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  5. Volz HP, Gleiter CH. Monoamine oxidase inhibitors. A perspective on their use in the elderly. Drugs Aging. 1998 Nov;13(5):341-55. http://www.ncbi.nlm.nih.gov/pubmed/9829163
  6. Drugs, Supplements, and Herbal Information. Medlineplus.A service of the U.S. National Library of Medicine and U.S. National Institutes of Health http://www.nlm.nih.gov/medlineplus/druginformation.html
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