Treating Psoriasis With Injections

By

Aaron Mangold, MD

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Injection

Treatment for psoriasis and many other inflammatory diseases was revolutionized with the introduction of biologics. But to understand how groundbreaking these types of drugs are for psoriasis, it’s important to look at how the condition was treated in the past.


Before Biologics

Psoriasis is a chronic, inflammatory skin condition characterized by red, scaly plaques that typically show up on the knees, elbows and scalp. Psoriasis is characterized by over activity of certain parts of the immune system. Before biologics, patients were often treated using non-specific immunosuppressants that would knock out many parts of the immune system. Drugs most commonly used were cyclosporine and methotrexate, as well as drugs that are toxic to the blood cells like hydroxyurea. It’s almost like using a cannon when all that was needed was a sling shot.

Biologic medications have shown great success in helping psoriasis patients clear their skin. However, sometimes it’s necessary to switch to a new biologic—and that’s okay.

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