In short, yes. However, the reality is a little more complex. That’s because while stress can worsen the disease, rheumatoid arthritis (RA) can create stress for you. Stress is especially tough on people with autoimmune diseases such as RA. Some of the pathways involved in your body’s stress response are the same ones involved in autoimmune disease. For people with RA, stress releases chemicals that can trigger flare-ups, along with inflammation and pain. RA as Internal Stressor In addition, RA can affect your body’s production of the stress-related chemical cortisol. In other words, RA is a type of internal stressor. With time, stress chemicals like cortisol may increase your risk for serious health conditions such as heart disease, obesity, and depression. These problems can lead to even more stress. As you likely already know, you may feel stressed because of your RA symptoms. No one likes moving slowly, and stiff joints can make it difficult to move around and get places on time. It can be stressful when daily activities or hobbies you love to do feel difficult or painful—or even seem impossible. Get the Best of Stress Just because you have RA doesn’t mean you have to feel stressed all the time. There’s plenty you can do to control the stress in your life and reduce its impact on your well-being. Here are five ways 1. Exercise. It can help with depression, anxiety, and sleep. Physical activity can even increase levels of chemicals in your body that improve your mood. 2. Breathe deeply. To promote relaxation, practice deep breathing, in through the nose and out through your mouth. Feel your belly rise and fall as you breathe. 3. Talk it out. Telling someone about negative emotions you’re experiencing can help relieve stress. If you don’t feel comfortable talking about these things, write them down in a journal. 4. Embrace the outdoors. Spending time in nature can boost your mood and quell stress. Take a hike or scenic drive. Enjoy a picnic. Plant a garden. 5. Get organized. At the end of each workday, create a to-do list for the following day. This can help you leave work behind so you can enjoy the rest of your day. Key Takeaways For people with RA, stress releases chemicals that can trigger flare-ups, along with inflammation and pain. In addition, RA can affect your body’s production of the stress-related chemical cortisol, increasing your risk for serious health conditions such as heart disease. There’s plenty you can do to control the stress in your life, including exercise, deep breathing, and spending time outdoors.