Kidney Cancer: 7 Things to Know

Doctor William C Lloyd Healthgrades Medical Reviewer
Medically Reviewed By William C. Lloyd III, MD, FACS
Written By Ashley Festa on February 24, 2021
  • Senior man
    Risk Factors and Early Detection of Kidney Cancer
    As with most cancers, catching kidney cancer in the early stages improves the person’s chance of survival. In fact, if it’s detected in stage I, patients have more than an 80% chance of survival, meaning they live at least five years beyond their cancer diagnosis. A complete cure is a reality in some cases. Because treatments are always improving, the kidney cancer survival rate may get even better with time. The more you know about this disease, the more prepared you’ll be to fight it should you or a loved one ever face a kidney cancer diagnosis.
  • Male friends
    1. Men are twice as likely to get kidney cancer.
    Age also plays a big part in whether someone will develop this disease. Most people are in their 60s when they receive a kidney cancer diagnosis. Doctors rarely find kidney cancer in people younger than 45 years old. White Americans are slightly less likely than African Americans or American Indians to develop renal cell carcinoma, which is the most common type of kidney cancer in adults.
  • Man smoking
    2. Smoking and obesity are the biggest risk factors for kidney cancer.
    Other risk factors can be work related, such as being exposed to certain substances like asbestos, cadmium, some herbicides, and organic solvents. You can’t avoid some risk factors, such as a family history of kidney cancer and people with advanced kidney disease. But you can be more alert to a heightened risk of developing cancer and see your doctor every year to manage your health.
  • Back pain
    3. A mass on your back is a symptom of kidney cancer.
    The other most common symptom is blood in the urine. Depending on how big the tumor is, kidney cancer symptoms can also include swelling in the legs and ankles, lower back pain, low red blood cell count (anemia), fatigue, unexplained fever, or unexplained weight loss. These symptoms can also be caused by other conditions, so talk with your doctor to rule out other health problems.
  • Ultrasound
    4. Imaging tests can reveal kidney cancer.
    If your doctor feels a lump in your abdomen or back and suspects kidney cancer, he or she might order diagnostic imaging tests, such as a CT scan, MRI, or ultrasound. Each of these tests creates images of the inside of your body that can show whether you have a tumor on your kidney. Your doctor might also order an intravenous pyelogram (IVP). For this test, you’ll receive an injection of dye before getting X-rays of your kidneys.
  • Surgery
    5. Surgery (nephrectomy) is the most common treatment for kidney cancer.
    A surgeon might remove part or the entire kidney, especially if the cancer is in the first three stages. If a nephrectomy isn’t possible, other treatment options may include immunotherapy, targeted therapy, radiation therapy, or chemotherapy (chemo). Chemo and radiation therapy are less useful against kidney cancer than other types of cancer, so they are not usually the first course of treatment. Your options for treatment will depend on your age, overall health, and the stage of kidney cancer.
  • Man examines hair
    6. There are side effects to every treatment option.
    Pain and swelling are the most common side effects of surgery. With targeted therapy, immunotherapy, or radiation therapy, you might experience a rash, nausea, diarrhea, and fatigue, among other symptoms. Chemotherapy can cause hair loss, nausea and vomiting, fatigue, mouth sores, diarrhea, or constipation. Cancer specialists always weigh the expected benefits of treatment with the severity of potential side effects when planning kidney cancer treatment.
  • Senior yoga
    7. Lifestyle changes can reduce your risk of kidney cancer.
    Because smoking, obesity, and high blood pressure are big risk factors for kidney cancer, it’s important to get these health conditions under control. Not smoking, or quitting if you smoke, helps prevent a long list of health problems, including cancer. If you have high blood pressure, talk with your doctor about strategies to lower it. You can’t always prevent kidney cancer, but making healthy lifestyle changes can reduce your risk.
Kidney Cancer | Kidney Cancer Symptoms | Renal Cell Carcinoma
  1. Kidney Cancer: Symptoms and Signs. Cancer.net. http://www.cancer.net/cancer-types/kidney-cancer/symptoms-and-signs
  2. Kidney Cancer. National Kidney Foundation. https://www.kidney.org/atoz/content/kidneycancer
  3. Survival rates for kidney cancer by stage. American Cancer Society. http://www.cancer.org/cancer/kidneycancer/detailedguide/kidney-cancer-adult-survival-rates
  4. What are the key statistics about kidney cancer? American Cancer Society. http://www.cancer.org/cancer/kidneycancer/detailedguide/kidney-cancer-adult-key-statistics
  5. Signs and symptoms of kidney cancer. American Cancer Society. http://www.cancer.org/cancer/kidneycancer/detailedguide/kidney-cancer-adult-signs-and-symptoms
  6. Treatment choices by stage for kidney cancer. American Cancer Society. http://www.cancer.org/cancer/kidneycancer/detailedguide/kidney-cancer-adult-treating-by-stage
  7. How is kidney cancer treated? American Cancer Society. http://www.cancer.org/cancer/kidneycancer/detailedguide/kidney-cancer-adult-treating-general-info
  8. Kidney Cancer. Mayo Clinic. http://www.mayoclinic.org/diseases-conditions/kidney-cancer/basics/prevention/con-20024753
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Last Review Date: 2021 Feb 24
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