The ABCs of Diabetes Control

Content provided by the Faculty of Harvard Medical School
Excerpted from a Harvard Special Report
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The Best Shoes for Diabetics

Finish off an outfit with omfortable shoes or boots and you can prevent sores, nerve damage and even amputation.

Because diabetes raises your risk of heart disease by four to five times compared with people without the disease, you should pay close attention to factors that can put you at greater risk for heart trouble. These are often referred to as the " ABCs":

  • Hemoglobin A1c blood sugar test

  • Blood pressure

  • Cholesterol.

A diagnosis of type 2 diabetes doesn’t need to ruin your life; in fact, it can change it for the better. With the right lifestyle changes, you can even avoid taking diabetes medication. These type 2 patients share how they cook, exercise, and relax their way to better health.

Medical Reviewer: William C. Lloyd III, MD, FACS Last Review Date: Aug 13, 2015

What is Toujeo® (insulin glargine injection) 300 Units/mL?

Prescription Toujeo® is a long-acting insulin used to control blood sugar in adults with diabetes mellitus.
• Toujeo® contains 3 times as much insulin in 1 mL as standard insulin (100 Units/mL)
• Toujeo® is not for use to treat diabetic ketoacidosis
• Toujeo® should not be used in children

Important Safety Information for Toujeo® (insulin glargine injection) 300 Units/mL

Do not take Toujeo® if you have low blood sugar or if you are allergic to insulin or any of the ingredients in Toujeo®.

Do NOT reuse needles or share insulin pens even if the needle has been changed.

Before starting Toujeo®, tell your doctor about all your medical conditions, including if you have liver or kidney problems, if you are pregnant or planning to become pregnant or if you are breastfeeding or planning to breastfeed.

Heart failure can occur if you are taking insulin together with certain medicines called TZDs (thiazolidinediones), even if you have never had heart failure or other heart problems. If you have heart failure, it may get worse while you take TZDs with Toujeo®. Your treatment with TZDs and Toujeo® may need to be changed or stopped by your doctor if you have new or worsening heart failure. Tell your doctor if you have any new or worsening symptoms of heart failure, including:
• Shortness of breath
• Swelling of your ankles or feet
• Sudden weight gain

Tell your doctor about all medications you take, including OTC medicines, vitamins, and supplements, including herbal supplements.

Toujeo® should be taken at the same time once a day. Test your blood sugar levels daily while using insulin, including Toujeo®. Do not make changes to your dose or type of insulin without talking to your doctor. Verify you have the correct insulin before each injection. Your dose for Toujeo® may be different from other insulins you have taken. Any change of insulin should be made cautiously and only under medical supervision.

Do NOT dilute or mix Toujeo® with any other insulin or solution. It will not work as intended and you may lose blood sugar control, which could be serious. Use Toujeo® only if the solution is clear and colorless with no particles visible.

Toujeo® (insulin glargine injection) 300 Units/mL

While using Toujeo®, do not drive or operate heavy machinery until you know how Toujeo® affects you. Don’t drink alcohol or use other medicines that contain alcohol.

The most common side effect of any insulin, including Toujeo®, is low blood sugar (hypoglycemia), which may be serious and can be lifethreatening. Severe hypoglycemia may cause harm to your heart or brain. Symptoms of serious low blood sugar may include shaking, sweating, fast heartbeat, and blurred vision.

Toujeo® may cause serious side effects that can lead to death, such as severe allergic reactions. Get medical help right away if you have:
• A rash over your whole body
• Shortness of breath
• Swelling of your face, tongue, or throat
• Extreme drowsiness, dizziness, or confusion
• Trouble breathing
• Fast heartbeat
• Sweating

Toujeo® may have additional side effects including swelling, weight gain, low potassium, and injection site reactions which may include change in fat tissue, skin thickening, redness, swelling, and itching.

Toujeo® SoloStar® is a disposable prefilled insulin pen. Talk to your doctor about proper injection technique and follow instructions in the Instruction Leaflet that comes with the pen.

Please see link below for Full Prescribing Information for Toujeo®

Prescribing Information | Important Safety Information
© 2002-2015 sanofi-aventis U.S. LLC. All rights reserved. | US.GLT.15.07.042

The treatment goals for people with diabetes are more stringent than those for people without diabetes. The good news is that lifestyle changes — and weight loss in particular — to improve your blood sugar usually will have a beneficial effect on the other values as well.

Optimal ABC markers for most people with diabetes
Less than 7%
Blood pressure
Less than 130/80 mm Hg
LDL (bad) cholesterol
Less than 100 mg/dL
HDL (good) cholesterol
More than 40 mg/dL in men or 50 mg/dL in women
Last Review Date: May 30, 2014

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